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Evans was then working with teratocarcinomas a type of tumor , which are of interest because they contain pluripotent stem cells known as embryonal carcinoma, [EC] cells from which all the differentiated cell types in the tumor arise.
During the two years she spent working in Evans' laboratory, Martin devised a protocol for isolating and maintaining EC cells in the undifferentiated state and for differentiating them in vitro.
This work  laid the groundwork for the future isolation of pluripotent stem cells from normal mouse and human embryos. In , Martin and her husband returned to Berkeley, where he took up a faculty position at UCB and she began a year of postdoctoral work with Charles J.
During this period she and her colleagues demonstrated that female EC cells had two active X chromosomes and could be used to study X-chromosome inactivation in vitro.
In Martin joined the UCSF faculty and established her own laboratory, which was active until Her first major accomplishment was the isolation of pluripotent stem cells from normal mouse blastocysts.
Subsequently, using sophisticated genetic methods that she helped to pioneer, Martin and her colleagues demonstrated the importance of FGF signaling in the development of many organs including the limb.
She also was responsible, in collaboration with a software engineer, Jonathan Scoles, for the development of a database that provides a description of all the genetically altered mice housed at UCSF.
This online resource helps researchers determine if mice carrying a particular genetic alteration are available at UCSF and to find out whom to contact about the possibility of obtaining them.
Access to this information has saved investigators considerable time and money in acquiring mouse models for their studies and been a stimulus to collaboration between researchers.
She has delivered numerous special lectures, including the George W. Brumley Jr. From Wikipedia, the free encyclopedia.
American biologist. This biography of a living person needs additional citations for verification. Please help by adding reliable sources.
Contentious material about living persons that is unsourced or poorly sourced must be removed immediately , especially if potentially libelous or harmful.
J; Kaufman M.I would vouch for her with my life. Where did you get the idea for your most recent book? She also was responsible, in collaboration with a software engineer, Jonathan Scoles, for the development of a database Gale Martin Gametwiste a description of all the genetically altered mice housed at UCSF. This is the Australien Vs Neuseeland for you! Society for Developmental Biology. Jeannie and Louis. Gale Martin entered a giveaway. In Martin joined the UCSF faculty and established her own laboratory, which was active until You wait all of June and July for zucchini. Nov 16, AM. I know what youre thinkingToto never wore a leash in The Wizard of Oz. Want to Read Currently Reading Read. Martin did her doctoral work in the laboratory of Harry Rubin, where she pursued several projects aimed at elucidating the mechanisms that control the growth of fibroblasts in vitro.